We have noticed the packet drop on all of our HP BL460c Gen 9 \ Gen 10 across the region which is running ESXi, 6.7.0, 16316930 and the Network adapter presently installed on the server is HPE FlexFabric 10Gb 2-port 536FLB Adapter which is Qlogic Adapter.
Version which comes with the HP custom image includes the qfle3 driver version 1.1.6.0-1OEM.650.0.0.4598673 and We have tried updating the driver \ firmware of the HP Enclosure \ OA \ Virtual Connect to the below versions but didn’t fix the issue.

OA Firmware : 4.96
https://support.hpe.com/hpsc/swd/public/detail?swItemId=MTX_8e583ffa28874a53aa272b959b
3.. Upgrade the Virtual connect firmware on one switch and another switch.
HP Virtual Connect Firmware: 4.85
https://support.hpe.com/hpsc/swd/public/detail?swItemId=MTX_f99f0bc5bfc4414aac021f81af#tab3
Solution:
After a lot of options tried, HP has recommended installing the below driver version and packet drop issue has been fixed.
https://support.hpe.com/hpsc/swd/public/detail?swItemId=MTX_fca9a16a601345919247b0c240#tab-history.
[root@esx106:~] esxcli software vib install -v “/cp039955/QLogic-Network-iSCSI-FCoE-v2.0.102-14793946/QLogic-Network-iSCSI-FCoE-v2.0.102-offline_bundle-14793946/vib20/qfle3/QLC_bootbank_qfle3_1.0.87.0-1OEM.670.0.0.8169922.vib”
Installation Result
Message: Host is not changed. Reboot is pending from previous transaction.
Reboot Required: true
VIBs Installed:
VIBs Removed:
VIBs Skipped: QLC_bootbank_qfle3_1.0.87.0-1OEM.670.0.0.8169922

I think as per the ESXi Patch advisory it is mentioned QFLE3 is 1.0.50.11-9vmw.670.0.0.8169922 so we need to have something near to the version and once installed the driver recommended by HP which is 1.0.87.0-1OEM.670.0.0.8169922 fixed the issue for us.

How did you see the packet drop? What tool were you using?
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esxcli network nic stats get -n vmnic0 by running this command in ESXi for all the nics we can find the stats of the packets and also noticed it in vROPs ..
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https://support.hpe.com/hpesc/public/docDisplay?docId=emr_na-a00109978en_us
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